About Die Off

Candida Die-off: Your Healing Friend and Foe

by Tarilee Cornish, Certified Nutritional Practitioner


Die Off

Candida Related Complex (CRC) is a condition involving an overgrowth of yeast. "Die-off" is a term used to describe the experience caused by the death of a large number of pathogenic organisms (like yeast.) In clinical settings, the phenomenon may be referred to as a Herxheimer reaction.


The death of the pathogens is usually caused by remedies or drugs that are antagonistic to the organism, i.e. anti-fungal nutraceuticals or herbal remedies.


Living yeast, when at unhealthy levels, can cause a myriad of constant symptoms by releasing toxic metabolic by-products into the body. Unfortunately, when anti-fungal treatment is begun, they release even larger amounts of these toxins, (or mycotoxins, if from fungus.)


In the case of CRC, once yeast populations in the intestines and/or systemic yeast levels have grown to the point that it causes symptoms, it is crucial to a full recovery that the yeast population is reduced to normal or even, for susceptible individuals, to below normal levels through the use of an anti-Candida diet and supplementary anti-fungal agents. Unfortunately, the catch is that the phenomenon of Die Off is almost always a part of any successful yeast reduction program.


Causing discomfort on their way out

Die Off symptoms can be felt for as long as it takes the body to clear out the toxins released by dead and dying yeast cells, (which create further waste that then needs to be flushed out.) As the toxins circulate in the bloodstream they can strain the eliminative capacities of the liver, kidneys, colon and lymph as they make their way out of the body, producing uncomfortable symptoms. Depending on the individuals level of overall health, symptoms may last a few hours up to a few days.


Feeling worse before you feel better

Generally speaking, most people experience die-off as an exaggeration of their existing Candida-related symptoms or as a worsening of chronic health conditions.

Providing there is no other illness or intolerance at play, feeling some symptoms worsen a bit after beginning the WholeApproach Candida program can be seen as positive as it helps to confirm both the presence of Candida and the effectiveness of the anti-fungal you are using.


Unique to each Person

Die-off is experienced differently by each person.  Most people experience die-off at some point in their recovery. There really is, however, no sure way to predict what point or to what degree one is likely to feel it.


Some start the program and feel better almost immediately, noticing positive effects such as increased energy, better mental focus, better elimination, etc. For these folks, the die-off experience may be minimal or may occur a few weeks into the program. Others start their yeast reduction program and experience diet off symptoms right away.


The die-off reaction can be felt for some people after simply changing their diet to a more pure, healthy diet that does not feed the yeast (even before starting on anti-fungals). It is unclear whether the symptoms experienced with diet alone are die off from the yeast dying due to starvation or if this experience is better explained as a general detoxification phenomenon as described in the article about Healing Crises. However, it is periodically reported and so is a reality for some, either way.


Die Off Symptoms

Common symptoms of Die Off include flu-like symptoms (stuffiness, headache, general aches and pains), skin rashes, vaginal irritation/discharge, numbness, mental confusion, fatigue, brain fog, constipation, and/or diarrhea. Mental and emotional symptoms such as irritability, anxiety or depression are also common.


Die Off Duration

Die off generally lasts from one day to a week but can last longer for highly sensitive individuals or if anti-fungal treatment is rushed through aggressive dosing. It is likely that Die Off will come and go throughout the program and is especially likely to occur during the first weeks of a new Phase of the Whole Approach program.


As you reduce the levels of yeast present to die off, you will start to feel better. Also, as your body becomes stronger, and you clear out a certain amount of the yeast related toxicity, your body will be better able to deal with die off. This additionally helps to reduce your die-off symptoms


Pulling Toxins Out

The products that make up the Whole Approach product protocol are selected partially for their ability to absorb the mycotoxins which cause the symptoms of Die Off. Both the Psyllium seed and husk blend and the Bentonite Liquid clay are effective at absorbing these toxins and thus reducing the severity of symptoms that may be felt in other anti-fungal protocols.

Generally speaking, the severity of symptoms depends upon several conditions including: one's overall health; strength of their immune system; degree of Candida infestation; environmental and emotional stress; how gently the treatment is approached and how complete and effective the overall self-care


Managing Die-Off


Candida most commonly colonizes the sides of the colon. It typically thrives behind and inside any build-up of fecal waste. Where there is a large amount of fecal build-up or intestinal mucous, die-off may be delayed or prolonged. It can take some time for the WholeApproach Program to scrub away at the wastes so that the anti-fungals are able to exert their full effect on the colonized yeast or fungi.


Go Slowly

It's important to keep this in mind as you time your dosage of anti-fungal. It's helpful to give your body time to adjust to each increase in anti-fungal as your accumulative response might not show for up to a week. Carefully observe how you respond to the most recent increase before adding the next. If Die Off symptoms emerge it is advisable to ease off on anti-fungal intake temporarily while symptoms subside.


Also, be sure to start each new anti-fungal phase with the use of a very low dose. You can increase it gradually, according to your response. If you have moderate to severe die-off symptoms you can cut back to reduce the number of dead yeast cells and the amount of toxic waste material your body has to cope with.


Prevent Die Off

The best way to deal with Die Off is to prevent the symptoms from occurring in the first place. More die-off symptoms don't necessarily indicate that more yeast is being killed, just that your eliminative organs are becoming overwhelmed. Rushing die off is stressful for your body and not conducive to healing. In most cases, slow, gradual yeast elimination process is best.



Not too much, not too little

The art of feeling the best you can through a Candida purge involves learning to manipulate the die-off process through body and mood awareness. Eventually you'll get used to how it feels to be detoxifying healthfully and you can strive to maintain this feeling without suffering through symptoms. You want to use enough product to be sure you are effectively reducing the yeast but not so much that you feel ill.


The right anti-fungal amount for you, is the amount that keeps the symptoms just 'at bay', or just 'below the surface.' Some experimentation will be required throughout your program as you continually 'feel out' what amount is just enough without suppressing your body's healing abilities. If you overdo it, you may need to take a break for a few days or more while your body cleanses.

You will be rewarded with faster recovery times when you proceed with your Candida purge at a rate that your digestive, eliminative and immune systems can comfortably cope with.


Die-off crisis

If you experience a Die Off crisis, don't criticize yourself for making a mistake. It's all part of the learning about your body and its cleansing process . If you find you have pushed your body too hard and you are feeling like you have Die Off symptoms, you'll want to temporarily stop using any anti-fungal and to drink lots of purified water. You may also wish to consider Daily Detox Tea as it can help to flush toxins through your blood, liver, lymph, and kidneys.


Other gentle detoxification supports that may help include Dr Ron's Buffered Vitamin C, , spirulina or chlorella, non-sweet vegetable juices (especially green juices) and eating extra vegetables at your meals, preferably raw, if your digestion does well with it.


One of my favourite herbs is turmeric.I buy a high quality, organic powder and mix a teaspoon of it with a bit of lemon juice, water and stevia (just enough to get it down as it's not the most 'gourmet' drink).


Turmeric  supports the liver in detoxification and alkalizes the body to help it rebalance. Asalways, before using any herbs mentioned here, make sure to do your research andbe vigilant about any contraindications your condition may indicate.


When die off symptoms subside, you can begin to gradually increase the anti-fungal dosage again over a few days or weeks to the level that you were at before the crisis. From there, you can continue to proceed to the recommended maximum dosage according to how you feel. If you never reach the full dosage but finish the three-month phase, this is fine and you can just move on to the next phase.


Deciphering Die Off

You may find yourself wondering if your symptoms are a result of the living yeast or the dying yeast, or both. However, it's important not to miss other serious conditions because you incorrectly dismiss them as Die Off.


If your crisis or symptoms are severe, please consider the possibility that they may be caused by something other than Die Off. Consult with your physician. Although your physician may not understand or be aware of the healing strategies that you are working with, they will hopefully be willing to insure there are no other medical conditions at play.


The Winding Road of CRC Recovery

Please be reassured that the process of treating CRC doesn't necessarily yield linear results. The recovery process involves a complex spiral of steps - killing off yeast, clearing the by-products, strengthening the body, killing off more yeast, clearing the by-products, and so on.

You can trust, however, that no matter what is happening, your body never stops working hard to cleanse, repair, and balance itself. The wisdom of the human body doesn't follow an exact schedule and our organs are not always consistently successful in meeting the challenges that face them. Hormone transitions (for women), environment, diet and our mental/emotional health can all affect our body's ability to cope with mycotoxins.. Sometimes it's complex to understand what is happening with our health. It will never be possible to know exactly what is happening at any given time. However, the use of a detailed health and diet diary can help tremendously as we try to keep track of our healing efforts and our responses to themincluding any patterns that may emerge.


Tracking your Successes

Filling out the WholeApproach Questionnaire on a weekly basis is a great way to track your progress with both diet and anti-fungal protocols. It will provide retrospective on the improvements or setbacks of the last week. This will help you assess yourrecent dietary and/or natural medicine strategies so you can consider whether . your effortsmade you feel better or worse 


Confidence and Clarity

The more detailed and organized your records and observation are, the more likely you will be successful in learning how to manage your health well. You'll feel more confident in your choices and stay aware enough to adjust you approach when necessary. 


Letting Go

All this being said about tracking and understanding, be aware that you can experience stress if you try too hard to understand everythingt. At some points in your program it may be best to just accept your experience of uncertainty. A calm mind facilitates lower inflammation, greater detoxification and more effective immune function If you need medical supervision take a look at this page which offers advice on finding the practitioner that is right for you. And, if you're feeling the need to share but don't have a supportive network, remember you can find support through your peers and our moderators at WholeApproachForum.com


Severe CRC

In the case of severe CRC, extreme sensitivity and immune weakness is common. In these cases it is crucial to remain aware of how your body is coping and be alert to conditions that may require immediate medical attention. You and your health diary have valuable information to decipher what's going on in your body. However you may at times need a medical doctor or Naturopathic Doctor to help you review this information and/or to perform some diagnostic tests to help you find your way.



Dealing with yeast die-off can be challenging and complex. To stay on track throughout your healing process, remember the following key points:


Don't rush the process or you will overwhelm your eliminative organs with toxins from dying yeast.


If/when you experience die-off symptoms, manage your diet and anti-fungal product dosages to minimize the symptoms and clear out potential waste build up.


Strategies include discontinuation of the anti-fungal, increasing water and vegetable intake and using Dr Ron's Buffered Vitamin C Plus and Daily Detox Tea.


Die-off reactions that are too uncomfortable can cause you to doubt your progress and may be confused with other health issues.


To prevent doubt and confusion, in addition to going slowly, keep a detailed record to help improve your decision-making and ability to discern what is happening in your body,



These strategies in combination with the WholeApproach Candida treatment protocol, will improve your progress towards renewed health and vigor. If you want assistance through your program or with anything you read on this site, please post questions on the Whole Approach forum.




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Disclaimer: Information provided on the Whole Approach website, forum or blog has been obtained from a variety of resources. It is provided for educational purposes only. The information provided by Whole Approach, WholeApproach Representatives, including Tarilee Cornish, should not be considered diagnostic or medical advice. None of the information provided by Whole Approach is intended to replace the guidance of your personal health care practitioners and/or physician. Please consult your licensed medical or naturopathic physician before beginning, or making changes to your supplement, diet or exercise protocol.