Dr Perlmutter is an interesting neuroscientist. You can always count on him to give some great reasons to help us stay off sugar, hard as that may be.
Here's an interesting article presenting an explanation of recent data which "shows that sugar can harm us in a place we didn’t expect, by actually attacking our DNA.new data shows that sugar can harm us in a place we didn’t expect, by actually attacking our DNA."
"...one of the major ways we can change our DNA is by diet. For example, a study published in 2008 showed that exposing mice brains to as little as 6 hours of high blood sugar led to epigenetic changes that increased risk of vascular damage. These changes lasted even after 6 days of normal blood glucose, representing long-term damage after just a short blast of sugar."
He goes on to explain how "high blood glucose may damage our telomeres; the ends of our DNA code. Considering that an undamaged telomere may be protective against cancer, death, and the very act of aging, any process that harms telomeres could put us at substantial risk. Data from the Journal of Nutrition, Health and Aging found that the higher the blood sugar, the more damage caused to the telomere and its associated DNA."
And for me, I found this part the most motivating of all....
..." researchers showed that short periods of high blood glucose led to worse long term vascular changes than did sustained high blood glucose (a scary thought for the carbohydrate binger). "
Some practitioners say that you can eat whatever you want 10% of the time. I don't believe this as I think that we can do a lot of sabotaging in one in ten days or one hour out of a ten hour eating window. Eating sugar can also apparently change the make up of the microbes in our gut, and, the more of some times of microbes we have, the more we will crave sugar.
The bottom line is that it is best to find a way not to feed them in the first place - yeast or the sugar-loving bacteria either.